
The Search For Maximal Wellness
The pursuit of optimal health and anti-aging strategies has led to many innovative solutions across many wellness categories. A demand for personalized approaches to address individual needs and preferences has also gained traction. On an individual basis, wellness is an active process, self-directed at achieving the fullest potential physically, emotionally, spiritually, socially, and economically. Combining compounded GLP-1s and hormone therapies has enabled a synergistic effect, promoting a more holistic and effective approach to health. Explore the many benefits of these modalities in maximizing overall wellness.

The benefits of GLP-1s
Glucagon-like peptide-1 (GLP-1) medications have attracted a great deal of attention in the treatment of type 2 diabetes mellitus (T2DM). Mimicking the GLP-1 hormone released from the intestine following a meal, GLP-1s stimulate the pancreas to release insulin. Many studies have demonstrated improved glycemic control with HbA1c reductions of 0.8%-1.5%. Additionally, a meta-analysis revealed a 14% reduction in cardiovascular death, nonfatal MI, and nonfatal stroke. GLP-1s were shown in a retrospective cohort study to reduce body weight by 5.9% at 3 months and 10.9% at 6 months in overweight and obese participants measured by a body mass index (BMI) of 27 or 30, respectively.
What happened to my hormones?
Hormone levels naturally decline with age. The most prominent hormones include estrogen and testosterone. Age-related declining hormones contribute to a variety of changes in both men and women. Menopause triggers hot flashes, sleep disturbances, mood changes, decreased bone mass, and lean body mass. Andropause causes decreased libido, energy, muscle mass, and sleep issues. Both conditions lead to increased fat deposition. Hormonal replacement therapy (HRT) aims to adjust hormone levels that are imbalanced, augmenting the aforementioned symptoms and improving health and quality of life.
Personalized compounding solutions
Compounding, the process of preparing customized medications, furnishes a unique option for individuals with various needs. Customization is the key factor that enables compounders to tailor therapies to individual needs, sensitivities, and preferences. Formulating compounds that are specifically developed for a patient affords medications that are better tolerated and effective. Additionally, medications are accessible to a broader population than commercially available drugs, expanding treatment options and improving patient outcomes. Personalized compounding also offers tailored medication dosage requirements, ensuring optimal treatment and minimizing the risk of adverse effects. Flexibility in administration is also the hallmark of compounding, providing medications in a variety of forms and dosages to suit individual needs.
The synergy of compounded GLP-1s and hormones
The search for optimal health and well-being has led to innovative solutions, including personalized approaches that accommodate individual needs and requirements. Combining compounded GLP-1s and HRT has provided a comprehensive treatment strategy for T2DM and weight loss. In fact, research indicates that participants taking both HRT and a GLP-1 experienced approximately 30% greater total body weight loss than non-hormone users. This synergistic effect highlights the potential benefits of combining treatments for individuals seeking to optimize health and well-being. Talk to a healthcare provider or compound pharmacist to discover the many benefits of the wellness trifecta.